HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19531213, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 665 Hs			1 1139
+	Hs
		1216104 SPD2A_HUMAN (3-650): 8.88e-37: 150: 16.74		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Mm
		104617 SH3K1_MOUSE (1-665): 2.78e-119: 373: 87.87		SYGP1_MOUSE (2-1138): 0: 768: 43.44
+	Hs
		222182 NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Mm
		104545 SRBS1_MOUSE (3-155): 1.1e-13: 77: 34.15		SYGP1_MOUSE (2-1138): 0: 768: 43.44
+	Mm
		104524 SRBS2_MOUSE (3-155): 3.33e-11: 68.9: 30.86		SYGP1_MOUSE (2-1138): 0: 768: 43.44
+	Hs
		863048 CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		635706 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		RASA1_HUMAN (91-623): 3.29e-142: 457: 26.50
+	Hs
		862791 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		593904 NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62		RASA1_HUMAN (91-623): 3.29e-142: 457: 26.50
+	Hs
		320222 SRBS2_HUMAN (3-155): 4.67e-11: 68.2: 30.86		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		637907 SPD2A_HUMAN (3-650): 8.88e-37: 150: 16.74		NF1_HUMAN (293-621): 8.78e-89: 317: 26.17
+	Hs
		637933 SH3R3_HUMAN (195-534): 4.22e-13: 74.7: 10.57		NF1_HUMAN (293-621): 8.78e-89: 317: 26.17