Interactor 1: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Interactor 2: HDAC6 (Q9UBN7)
Protein deacetylase HDAC6 (EC 3.5.1.-) (E3 ubiquitin-protein ligase HDAC6) (EC 2.3.2.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 11948178
Identification Methods affinity chromatography technology, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
GO:0040029 - epigenetic regulation of gene expression
GO:0141221 - histone deacetylase activity, hydrolytic mechanism
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 347
Hs

1 1215
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Last updated: 11Aug2025