Protein: HDAC3
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-)

Gene: HDAC3
Organism: Mus musculus
Interactions: 27
UniProt ID: O88895

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000132 - establishment of mitotic spindle orientation
GO:0000785 - chromatin
GO:0001222 - transcription corepressor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313132

MECP2
Methyl-CpG-binding protein 2

1

19

Small-scale

0.691

High

313122

NCOR1
Nuclear receptor corepressor 1

1

20

Small-scale

0.646

High

148632

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.618

High

313113

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

20

Small-scale

0.584

High

313127

HDAC4
Histone deacetylase 4

1

17

Small-scale

0.575

High

313125

NR2E1
Nuclear receptor subfamily 2 group E member 1

1

20

Small-scale

0.515

High

313111

CXA1
Gap junction alpha-1 protein

1

2

Small-scale

0.500

High

313126

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

18

Small-scale

0.484

High

205502

CFLAR
CASP8 and FADD-like apoptosis regulator

1

1

Small-scale

0.479

High

313109

PGK1
Phosphoglycerate kinase 1

1

2

Small-scale

0.479

High

313112

CCND1
G1/S-specific cyclin-D1

1

6

Small-scale

0.479

High

313115

PROX1
Prospero homeobox protein 1

1

3

Small-scale

0.479

High

313117

IRF7
Interferon regulatory factor 7

1

5

Small-scale

0.479

High

313118

GSC
Homeobox protein goosecoid

1

6

Small-scale

0.479

High

313120

RELB
Transcription factor RelB

1

20

Small-scale

0.479

High

313121

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.479

High

313130

DACH1
Dachshund homolog 1

1

2

Small-scale

0.479

High

313131

IKBA
NF-kappa-B inhibitor alpha

1

18

Small-scale

0.479

High

313110

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.458

High

236511

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

13

Small-scale

0.445

High

313114

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.445

High

313116

RORA
Nuclear receptor ROR-alpha

1

20

Small-scale

0.445

High

313119

TF65
Transcription factor p65

1

20

Small-scale

0.445

High

313123

LAP2B
Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma

1

3

Small-scale

0.445

High

313124

MEF2D
Myocyte-specific enhancer factor 2D

1

7

Small-scale

0.445

High

313129

NANOG
Homeobox protein NANOG

1

11

High-throughput

0.445

High

313128

Q6ZPV5
MKIAA1235 protein

1

4

Small-scale

0.437

High


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Last updated: 11Aug2025