HitPredict

Interactor 1: MTMR8 (Q96EF0)
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8 (EC 3.1.3.95) (Myotubularin-related protein 8) (Phosphatidylinositol-3-phosphate phosphatase)
Gene: MTMR8

Interactor 2: MTMR7 (Q9Y216)
Phosphatidylinositol-3-phosphate phosphatase MTMR7 (EC 3.1.3.64) (Inositol 1,3-bisphosphate phosphatase) (Myotubularin-related protein 7)
Gene: MTMR7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myotub-related~Myotub-related
Common GO terms GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0046856 - phosphatidylinositol dephosphorylation
GO:0052629 - phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 704
Hs

1 660
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Last updated: 11Aug2025