HitPredict

Interactor 1: LRCH3 (Q96II8)
DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3)
Gene: LRCH3

Interactor 2: DOCK7 (Q96N67)
Dedicator of cytokinesis protein 7
Gene: DOCK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.50	0.687

Property	Details
Experiments	29467281, 32203420, 35271311, 24255178, 28514442, 33961781, unassigned2213, unassigned3799
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 2140
+	Hs
		1338510 LRCH3_HUMAN (14-777): 1.19e-173: 520: 100.00		DOCK8_HUMAN (2-2139): 0: 2478: 55.69
+	Hs
		281538 LRCH4_HUMAN (46-413): 6.78e-60: 216: 52.67		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Hs
		1393340 LRCH3_HUMAN (14-777): 1.19e-173: 520: 100.00		DOCK6_HUMAN (2-2140): 0: 2420: 64.50
+	Hs
		1398868 LRCH1_HUMAN (2-193): 8.29e-28: 122: 25.52		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Hs
		1218309 LRCH2_HUMAN (3-198): 1.27e-21: 102: 20.90		DOCK7_HUMAN (1-2140): 0: 2782: 100.00
+	Hs
		281533 LRCH4_HUMAN (46-413): 6.78e-60: 216: 52.67		DOCK8_HUMAN (2-2139): 0: 2478: 55.69
+	Hs
		281536 LRCH4_HUMAN (46-413): 6.78e-60: 216: 52.67		DOCK6_HUMAN (2-2140): 0: 2420: 64.50
+	Hs
		1338529 LRCH1_HUMAN (2-193): 8.29e-28: 122: 25.52		DOCK8_HUMAN (2-2139): 0: 2478: 55.69
+	Hs
		1218299 LRCH2_HUMAN (3-198): 1.27e-21: 102: 20.90		DOCK8_HUMAN (2-2139): 0: 2478: 55.69
+	Hs
		1393347 LRCH1_HUMAN (2-193): 8.29e-28: 122: 25.52		DOCK6_HUMAN (2-2140): 0: 2420: 64.50
+	Hs
		1218305 LRCH2_HUMAN (3-198): 1.27e-21: 102: 20.90		DOCK6_HUMAN (2-2140): 0: 2420: 64.50
+	Hs
		1218316 LRCH2_HUMAN (3-198): 1.27e-21: 102: 20.90		DOCK5_HUMAN (303-859): 3.63e-76: 284: 15.15