Protein: LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein)

Gene: LRCH4
Organism: Homo sapiens
Interactions: 41
UniProt ID: O75427

Gene Ontology (top 5):
GO:0001765 - membrane raft assembly
GO:0005886 - plasma membrane
GO:0007399 - nervous system development
GO:0016605 - PML body
GO:0034123 - positive regulation of toll-like receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

281537

LRCH3
DISP complex protein LRCH3

2

19

High-throughput

0.726

High

281533

DOCK8
Dedicator of cytokinesis protein 8

4

12

High-throughput

0.696

High

281540

RTN4
Reticulon-4

2

3

High-throughput

0.633

High

281538

DOCK7
Dedicator of cytokinesis protein 7

4

12

High-throughput

0.626

High

281523

ISM2
Isthmin-2

1

1

High-throughput

0.618

High

281545

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

18

High-throughput

0.618

High

281515

RAB7A
Ras-related protein Rab-7a

1

6

High-throughput

0.618

High

281539

MDFI
MyoD family inhibitor

2

1

High-throughput

0.584

High

281525

RNK
Ribonuclease kappa

2

0

High-throughput

0.580

High

281522

VASN
Vasorin

1

20

High-throughput

0.575

High

281512

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

281531

KASH5
Protein KASH5

2

2

High-throughput

0.553

High

281532

DHB11
Estradiol 17-beta-dehydrogenase 11

2

1

High-throughput

0.553

High

281536

DOCK6
Dedicator of cytokinesis protein 6

2

12

High-throughput

0.543

High

281516

KR107
Keratin-associated protein 10-7

1

1

High-throughput

0.523

High

281517

KR108
Keratin-associated protein 10-8

1

1

High-throughput

0.523

High

281526

NT2NA
Notch homolog 2 N-terminal-like protein A

1

3

High-throughput

0.523

High

281530

FXL16
F-box/LRR-repeat protein 16

1

20

High-throughput

0.514

High

281546

SGT1
Protein SGT1 homolog

1

20

High-throughput

0.489

High

281544

MYO6
Unconventional myosin-VI

1

7

High-throughput

0.479

High

281520

H2B2F
Histone H2B type 2-F

1

3

High-throughput

0.470

High

281519

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

0

High-throughput

0.458

High

254681

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

227278

SPOP
Speckle-type POZ protein

1

2

Small-scale

0.439

High

281527

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

2

Small-scale

0.439

High

240283

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.437

High

281510

TAD2A
Transcriptional adapter 2-alpha

1

2

High-throughput

0.437

High

281534

ESR2
Estrogen receptor beta

1

18

High-throughput

0.437

High

281535

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.437

High

281541

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.437

High

281542

XPO7
Exportin-7

1

7

High-throughput

0.437

High

281543

FBW1B
F-box/WD repeat-containing protein 11

1

11

High-throughput

0.437

High

51274

ELOV7
Very long chain fatty acid elongase 7

2

0

High-throughput

0.316

High

281511

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.316

High

281528

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.316

High

281521

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.299

High

281513

CAH8
Carbonic anhydrase-related protein

1

0

High-throughput

0.282

High

281514

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

0

High-throughput

0.279

Low

281529

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

281518

TMED2
Transmembrane emp24 domain-containing protein 2

1

0

High-throughput

0.232

Low

281524

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025