HitPredict

Interactor 1: DOCK7 (Q96N67)
Dedicator of cytokinesis protein 7
Gene: DOCK7

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.50	0.682

Property	Details
Experiments	29467281, 32203420, 33961781, 35271311, 24255178, unassigned2213, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2140 Hs			1 728
+	Hs
		1338529 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH1_HUMAN (1-728): 5.65e-150: 455: 100.00
+	Hs
		281538 DOCK7_HUMAN (1-2140): 0: 2782: 100.00		LRCH4_HUMAN (6-165): 1.31e-21: 102: 18.52
+	Hs
		1218309 DOCK7_HUMAN (1-2140): 0: 2782: 100.00		LRCH2_HUMAN (3-165): 3.52e-19: 94.4: 13.94
+	Hs
		1393347 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH1_HUMAN (1-728): 5.65e-150: 455: 100.00
+	Hs
		1394185 DOCK7_HUMAN (1-2140): 0: 2782: 100.00		LRCH3_HUMAN (12-155): 1.88e-12: 72.8: 14.29
+	Hs
		281533 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH4_HUMAN (6-165): 1.31e-21: 102: 18.52
+	Hs
		1218299 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH2_HUMAN (3-165): 3.52e-19: 94.4: 13.94
+	Hs
		1338510 DOCK8_HUMAN (2-2139): 0: 2478: 55.69		LRCH3_HUMAN (12-155): 1.88e-12: 72.8: 14.29
+	Hs
		281536 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH4_HUMAN (6-165): 1.31e-21: 102: 18.52
+	Hs
		1218305 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH2_HUMAN (3-165): 3.52e-19: 94.4: 13.94
+	Hs
		1393340 DOCK6_HUMAN (2-2140): 0: 2420: 64.50		LRCH3_HUMAN (12-155): 1.88e-12: 72.8: 14.29
+	Hs
		1218316 DOCK5_HUMAN (303-859): 3.63e-76: 284: 15.15		LRCH2_HUMAN (3-165): 3.52e-19: 94.4: 13.94