HitPredict

Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: MTA2 (Q9R190)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1)
Gene: MTA2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 15920471, 16462733, 20404188, 19424149, 24240174
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0004407 - histone deacetylase activity
and 11 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 482
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024