HitPredict

Interactor 1: SYTL3 (Q99N48)
Synaptotagmin-like protein 3 (Exophilin-6)
Gene: SYTL3

Interactor 2: RB27A (Q9ERI2)
Ras-related protein Rab-27A (EC 3.6.5.2)
Gene: Rab27a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	11773082
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Mm			1 221
+	Hs
		902271 SYTL3_HUMAN (1-607): 2.63e-161: 476: 79.34		RB27A_HUMAN (1-221): 9.68e-86: 254: 95.93
+	Hs
		125994 SYTL3_HUMAN (1-607): 2.63e-161: 476: 79.34		RB27B_HUMAN (1-221): 1.33e-81: 244: 71.95
+	Hs
		902287 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RB27A_HUMAN (1-221): 9.68e-86: 254: 95.93
+	Mm
		1424410 SYTL4_MOUSE (1-606): 6.89e-141: 426: 29.45		RB27A_MOUSE (1-221): 1.78e-85: 254: 100.00
+	Hs
		126003 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RB27B_HUMAN (1-221): 1.33e-81: 244: 71.95
+	Mm
		1408946 SYTL4_MOUSE (1-606): 6.89e-141: 426: 29.45		RB27B_MOUSE (1-221): 5.21e-81: 242: 71.49
+	Hs
		976477 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RB11A_HUMAN (3-220): 7.49e-80: 239: 34.84
+	Hs
		902284 SYTL5_HUMAN (2-606): 1.17e-127: 393: 27.17		RB27A_HUMAN (1-221): 9.68e-86: 254: 95.93
+	Hs
		956731 SYTL3_HUMAN (1-607): 2.63e-161: 476: 79.34		RAB10_HUMAN (1-184): 1.04e-49: 162: 42.94
+	Hs
		126000 SYTL5_HUMAN (2-606): 1.17e-127: 393: 27.17		RB27B_HUMAN (1-221): 1.33e-81: 244: 71.95
+	Hs
		976443 SYTL5_HUMAN (2-606): 1.17e-127: 393: 27.17		RB11A_HUMAN (3-220): 7.49e-80: 239: 34.84
+	Hs
		630433 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RAB3A_HUMAN (2-192): 8.94e-57: 181: 43.98
+	Hs
		343187 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RAB3D_HUMAN (2-190): 1.76e-56: 180: 43.92
+	Mm
		989215 SYTL4_MOUSE (1-606): 6.89e-141: 426: 29.45		RAB3A_MOUSE (2-192): 9.54e-57: 181: 43.98
+	Hs
		630605 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RAB3B_HUMAN (2-190): 1.88e-54: 175: 43.92
+	Hs
		955988 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RAB8A_HUMAN (6-187): 9.23e-54: 172: 46.70
+	Hs
		1370773 SYTL4_HUMAN (1-606): 3.02e-142: 429: 29.79		RAB8B_HUMAN (6-192): 3.91e-53: 171: 44.39
+	Mm
		937173 SYTL4_MOUSE (1-606): 6.89e-141: 426: 29.45		RAB8A_MOUSE (6-187): 1.16e-53: 172: 46.70
+	Hs
		630431 SYTL5_HUMAN (2-606): 1.17e-127: 393: 27.17		RAB3A_HUMAN (2-192): 8.94e-57: 181: 43.98
+	Hs
		630588 SYTL5_HUMAN (2-606): 1.17e-127: 393: 27.17		RAB3B_HUMAN (2-190): 1.88e-54: 175: 43.92