HitPredict

Interactor 1: CNPY3 (Q9BT09)
Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)
Gene: CNPY3

Interactor 2: TLR10 (Q9BXR5)
Toll-like receptor 10 (CD antigen CD290)
Gene: TLR10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 278 Hs			1 811
+	Hs
		1148234 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		TLR1_HUMAN (19-785): 5.48e-105: 342: 48.77
+	Hs
		777250 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		ALS_HUMAN (26-574): 1.15e-69: 243: 17.60
+	Hs
		94395 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		D6RAP2_HUMAN (4-164): 1.52e-47: 168: 46.58
+	Hs
		1126001 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		LRC32_HUMAN (32-598): 2.22e-42: 166: 18.85
+	Hs
		1412989 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		TLR9_HUMAN (13-599): 7.25e-26: 116: 13.47
+	Hs
		252288 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		TLR5_HUMAN (2-334): 5.84e-15: 81.2: 15.74
+	Hs
		1412990 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		TLR8_HUMAN (1-206): 5.91e-13: 75: 16.67
+	Hs
		126333 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		TLR4_HUMAN (4-433): 1.57e-11: 70: 9.91
+	Hs
		458645 CNPY3_HUMAN (1-278): 9.7e-149: 419: 100.00		PGS2_HUMAN (17-165): 7.42e-10: 63.5: 27.68
+	Mm
		1297239 CNPY4_MOUSE (10-215): 4.24e-111: 322: 47.34		TLR4_MOUSE (4-470): 2.37e-10: 66.5: 13.38