HitPredict

Interactor 1: TRIM9 (Q9C026)
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)
Gene: TRIM9

Interactor 2: FBXW2 (Q9UKT8)
F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6)
Gene: FBXW2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Hs			1 454
+	Hs
		1420548 TRIM9_HUMAN (1-710): 0: 556: 100.00		FBW1A_HUMAN (24-313): 3.22e-59: 206: 18.03
+	Hs
		3431 TRIM9_HUMAN (1-710): 0: 556: 100.00		A0A0S2Z507_HUMAN (24-313): 7.06e-59: 205: 18.03
+	Hs
		85137 TRIM9_HUMAN (1-710): 0: 556: 100.00		B7Z3H4_HUMAN (24-313): 9.99e-59: 204: 18.03
+	Hs
		1420546 TRIM9_HUMAN (1-710): 0: 556: 100.00		FBW1B_HUMAN (24-308): 4.55e-56: 196: 19.00
+	Hs
		845322 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		LIS1_HUMAN (4-256): 2.4e-52: 183: 16.20
+	Hs
		222502 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		PLRG1_HUMAN (78-350): 2.01e-43: 161: 18.49
+	Hs
		1255421 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		TBL1R_HUMAN (221-452): 9.21e-32: 128: 16.05
+	Hs
		1255265 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		TBL1Y_HUMAN (220-452): 2.8e-31: 127: 16.87
+	Hs
		965045 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		WDR5_HUMAN (316-452): 5.63e-25: 106: 12.86
+	Hs
		1255786 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		NLE1_HUMAN (4-173): 3e-23: 103: 15.03
+	Hs
		1446848 TRI36_HUMAN (1-699): 2.13e-101: 328: 22.25		FBW1A_HUMAN (24-313): 3.22e-59: 206: 18.03
+	Hs
		1255005 TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43		SNR40_HUMAN (129-253): 8.56e-12: 68.2: 31.25
+	Hs
		1125178 TRI25_HUMAN (77-694): 9.13e-69: 239: 14.88		FBXW7_HUMAN (32-264): 1.01e-57: 203: 21.85
+	Hs
		1419264 TRI54_HUMAN (1-56): 5.41e-09: 60.6: 36.21		FBXW2_HUMAN (1-454): 1.17e-103: 317: 100.00
+	Hs
		261409 TRI25_HUMAN (77-694): 9.13e-69: 239: 14.88		TBL1X_HUMAN (220-452): 3.96e-32: 130: 15.23
+	Hs
		1089246 TRI26_HUMAN (1-153): 1.02e-26: 117: 13.73		FBXW7_HUMAN (32-264): 1.01e-57: 203: 21.85
+	Hs
		623597 RO52_HUMAN (1-164): 2.71e-23: 105: 15.24		FBW1A_HUMAN (24-313): 3.22e-59: 206: 18.03
+	Hs
		623473 RO52_HUMAN (1-164): 2.71e-23: 105: 15.24		FBXW7_HUMAN (32-264): 1.01e-57: 203: 21.85
+	Hs
		180894 TIF1A_HUMAN (9-588): 2.42e-66: 239: 12.33		SNR40_HUMAN (129-253): 8.56e-12: 68.2: 31.25
+	Hs
		623587 RO52_HUMAN (1-164): 2.71e-23: 105: 15.24		FBW1B_HUMAN (24-308): 4.55e-56: 196: 19.00