HitPredict

Interactor 1: ZYG1 (Q9GT24)
Probable serine/threonine-protein kinase zyg-1 (EC 2.7.11.1) (Zygote defective protein 1)
Gene: zyg-1

Interactor 2: ZYG1 (Q9GT24)
Probable serine/threonine-protein kinase zyg-1 (EC 2.7.11.1) (Zygote defective protein 1)
Gene: zyg-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.748

The method score is based on:

Property Details
Experiments 24980795
Identification Methods x-ray crystallography, molecular sieving, static light scattering, x ray scattering
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Polo_box_2~Polo_box_3
Common GO terms GO:0000278 - mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0004694 - eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 25 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 706
Ce

1 706
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025