Protein: ARHGP
Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF)

Gene: ARHGP, ARHGEF25
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q86VW2

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007411 - axon guidance

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

962227

RHOA
Transforming protein RhoA

2

20

Small-scale

0.799

High

424667

KPCG
Protein kinase C gamma type

1

15

Small-scale

0.647

High

955340

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.647

High

988495

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.647

High

1270882

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.647

High

1291782

RTN4R
Reticulon-4 receptor

2

1

High-throughput

0.628

High

1291785

COR2B
Coronin-2B

2

8

High-throughput

0.628

High

867946

GBRB2
Gamma-aminobutyric acid receptor subunit beta-2

2

0

High-throughput

0.602

High

179226

ARC1B
Actin-related protein 2/3 complex subunit 1B

2

5

High-throughput

0.571

High

1143183

PLEC
Plectin

2

10

High-throughput

0.571

High

1291777

LMO3
LIM domain only protein 3

1

10

High-throughput

0.536

High

682057

RBTN1
Rhombotin-1

1

9

High-throughput

0.489

High

171272

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

10

High-throughput

0.479

High

242170

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

299265

FLOT1
Flotillin-1

1

9

High-throughput

0.479

High

451199

NFL
Neurofilament light polypeptide

1

9

High-throughput

0.479

High

461665

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.479

High

582101

PGAM2
Phosphoglycerate mutase 2

1

4

High-throughput

0.479

High

616197

PGAM1
Phosphoglycerate mutase 1

1

4

High-throughput

0.479

High

999374

HBB
Hemoglobin subunit beta

1

2

High-throughput

0.479

High

1247494

POTEE
POTE ankyrin domain family member E

1

12

High-throughput

0.479

High

1291778

DNJC9
DnaJ homolog subfamily C member 9

1

4

High-throughput

0.479

High

1291780

FUBP3
Far upstream element-binding protein 3

1

4

High-throughput

0.479

High

1291781

NEB2
Neurabin-2

1

20

High-throughput

0.479

High

1291786

RTRAF
RNA transcription, translation and transport factor protein

1

1

High-throughput

0.479

High

1291776

PGAM4
Probable phosphoglycerate mutase 4

1

4

High-throughput

0.437

High

1291779

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

5

High-throughput

0.437

High

1291783

CCD86
Coiled-coil domain-containing protein 86

1

2

High-throughput

0.437

High

1014147

CBX1
Chromobox protein homolog 1

2

0

High-throughput

0.298

High

1291784

SLX9
Ribosome biogenesis protein SLX9 homolog

2

0

High-throughput

0.298

High


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Last updated: 11Aug2025