HitPredict

Interactor 1: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35671810
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~UQ_con
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1024 Hs			1 318
+	Hs
		982355 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2D2_HUMAN (10-156): 6.77e-70: 215: 28.00
+	Hs
		906816 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2D1_HUMAN (10-156): 1.34e-69: 214: 30.00
+	Hs
		957230 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2D3_HUMAN (10-156): 2.03e-68: 211: 28.00
+	Hs
		1324415 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2J2_HUMAN (1-150): 3.35e-63: 202: 39.87
+	Hs
		909408 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2E1_HUMAN (1-155): 4.54e-64: 202: 28.48
+	Hs
		1381217 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2E3_HUMAN (2-155): 1.58e-62: 199: 26.75
+	Hs
		1397302 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2E2_HUMAN (2-155): 4.94e-62: 197: 27.39
+	Hs
		884417 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UBE2A_HUMAN (7-154): 9.7e-61: 192: 21.85
+	Hs
		990999 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UBE2B_HUMAN (7-146): 1.16e-59: 189: 23.08
+	Hs
		952479 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2G2_HUMAN (7-142): 5.56e-58: 185: 26.00
+	Hs
		970230 HERC5_HUMAN (16-1024): 0: 1018: 100.00		UB2G1_HUMAN (15-148): 2.06e-56: 182: 25.83
+	Hs
		982169 UBE3A_HUMAN (363-1024): 0: 567: 23.66		UB2D2_HUMAN (10-156): 6.77e-70: 215: 28.00
+	Hs
		906647 UBE3A_HUMAN (363-1024): 0: 567: 23.66		UB2D1_HUMAN (10-156): 1.34e-69: 214: 30.00
+	Hs
		957065 UBE3A_HUMAN (363-1024): 0: 567: 23.66		UB2D3_HUMAN (10-156): 2.03e-68: 211: 28.00
+	Hs
		982320 WWP1_HUMAN (547-1024): 0: 556: 20.48		UB2D2_HUMAN (10-156): 6.77e-70: 215: 28.00
+	Hs
		906781 WWP1_HUMAN (547-1024): 0: 556: 20.48		UB2D1_HUMAN (10-156): 1.34e-69: 214: 30.00
+	Hs
		909309 UBE3A_HUMAN (363-1024): 0: 567: 23.66		UB2E1_HUMAN (1-155): 4.54e-64: 202: 28.48
+	Hs
		957197 WWP1_HUMAN (547-1024): 0: 556: 20.48		UB2D3_HUMAN (10-156): 2.03e-68: 211: 28.00
+	Hs
		131839 WWP2_HUMAN (547-1024): 0: 550: 19.68		UB2D1_HUMAN (10-156): 1.34e-69: 214: 30.00
+	Hs
		131840 WWP2_HUMAN (547-1024): 0: 550: 19.68		UB2E1_HUMAN (1-155): 4.54e-64: 202: 28.48