Protein: UB2G1
Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]

Gene: UB2G1, UBE2G1
Organism: Homo sapiens
Interactions: 36
UniProt ID: P62253

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

970212

RBX1
E3 ubiquitin-protein ligase RBX1

7

20

Small-scale

0.960

High

970232

AMFR
E3 ubiquitin-protein ligase AMFR

7

20

Small-scale

0.958

High

241294

PRKN
E3 ubiquitin-protein ligase parkin

6

20

Small-scale

0.940

High

647529

UBA1
Ubiquitin-like modifier-activating enzyme 1

4

20

Small-scale

0.885

High

970223

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

20

Small-scale

0.778

High

507779

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

20

Small-scale

0.768

High

970225

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

20

High-throughput

0.698

High

970211

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

15

Small-scale

0.692

High

898215

R144A
E3 ubiquitin-protein ligase RNF144A

1

20

High-throughput

0.691

High

970214

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

20

High-throughput

0.691

High

970217

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

Small-scale

0.647

High

970218

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

20

Small-scale

0.647

High

970219

CUL9
Cullin-9

1

20

Small-scale

0.647

High

970226

TRIM2
Tripartite motif-containing protein 2

1

20

Small-scale

0.647

High

970227

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

20

Small-scale

0.647

High

970230

HERC5
E3 ISG15--protein ligase HERC5

1

20

Small-scale

0.618

High

970234

RNF11
RING finger protein 11

1

20

Small-scale

0.618

High

970222

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

Small-scale

0.579

High

970221

IOD2
Type II iodothyronine deiodinase

2

0

Small-scale

0.577

High

970228

IL36G
Interleukin-36 gamma

1

1

High-throughput

0.536

High

561978

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.515

High

970213

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.515

High

970233

SHLB1
Endophilin-B1

1

2

High-throughput

0.515

High

246287

MARH6
E3 ubiquitin-protein ligase MARCHF6

1

19

Small-scale

0.501

High

421859

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

970215

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

7

Small-scale

0.501

High

970216

RC3H1
Roquin-1

1

4

Small-scale

0.501

High

970224

CRBN
Protein cereblon

1

2

Small-scale

0.501

High

970229

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

Small-scale

0.501

High

567344

TCTP
Translationally-controlled tumor protein

1

3

High-throughput

0.479

High

280569

PR40A
Pre-mRNA-processing factor 40 homolog A

1

15

High-throughput

0.470

High

970231

FBXL2
F-box/LRR-repeat protein 2

1

6

Small-scale

0.457

High

475193

CP3A4
Cytochrome P450 3A4

1

2

Small-scale

0.437

High

970220

RDH5
Retinol dehydrogenase 5

1

4

High-throughput

0.437

High

441531

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025