HitPredict

Interactor 1: SAV (Q9VCR6)
Scaffold protein salvador (Shar-pei)
Gene: SAV

Interactor 2: KIBRA (Q9VFG8)
Protein kibra
Gene: KIBRA

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	20159598
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	WW~WW
Common GO terms	GO:0043065 - positive regulation of apoptotic process GO:0045463 - R8 cell development GO:0045464 - R8 cell fate specification GO:0046621 - negative regulation of organ growth GO:0060090 - molecular adaptor activity and 1 others more... GO:0106037 - apicomedial cortex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 608 Dm			1 1288
+	Mm
		97724 E9PXB7_MOUSE (70-601): 4.37e-104: 335: 13.57		E9PXB7_MOUSE (32-207): 1.98e-47: 185: 24.18
+	Hs
		861788 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		SMUF1_HUMAN (25-238): 3.56e-58: 217: 18.18
+	Hs
		861785 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		SMUF2_HUMAN (4-238): 1.34e-48: 188: 16.41
+	Hs
		861512 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		YAP1_HUMAN (38-152): 3.39e-34: 140: 29.13
+	Hs
		861726 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		ITCH_HUMAN (47-200): 1.17e-30: 133: 23.38
+	Hs
		1437697 SMUF2_HUMAN (283-593): 3.15e-56: 204: 11.82		SMUF1_HUMAN (25-238): 3.56e-58: 217: 18.18
+	Hs
		861511 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		NEDD4_HUMAN (24-207): 1.8e-28: 126: 17.31
+	Hs
		862443 WWP1_HUMAN (100-606): 5.36e-77: 264: 12.96		YAP1_HUMAN (38-152): 3.39e-34: 140: 29.13
+	Hs
		132289 WWP1_HUMAN (100-606): 5.36e-77: 264: 12.96		WWP2_HUMAN (34-200): 2.54e-31: 135: 23.35
+	Hs
		1394608 WWP1_HUMAN (100-606): 5.36e-77: 264: 12.96		ITCH_HUMAN (47-200): 1.17e-30: 133: 23.38
+	Hs
		1437696 SMUF2_HUMAN (283-593): 3.15e-56: 204: 11.82		SMUF2_HUMAN (4-238): 1.34e-48: 188: 16.41
+	Dm
		1487324 NEDD4_DROME (88-601): 1.5e-79: 272: 15.63		SUDX_DROME (39-168): 3.58e-25: 115: 29.23
+	Dm
		1490413 SUDX_DROME (91-608): 1.49e-78: 269: 13.29		SUDX_DROME (39-168): 3.58e-25: 115: 29.23
+	Hs
		1430201 WWP1_HUMAN (100-606): 5.36e-77: 264: 12.96		WWP1_HUMAN (1-163): 7.16e-23: 108: 23.64
+	Hs
		639109 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		SYT1_HUMAN (675-835): 5.78e-13: 74.5: 17.68
+	Hs
		861735 NEDD4_HUMAN (71-601): 1.6e-84: 290: 15.59		NED4L_HUMAN (5-194): 7.3e-12: 72.3: 15.42
+	Hs
		862470 SMUF2_HUMAN (283-593): 3.15e-56: 204: 11.82		YAP1_HUMAN (38-152): 3.39e-34: 140: 29.13
+	Hs
		861781 SAV1_HUMAN (283-604): 7.39e-50: 179: 28.66		NEDD4_HUMAN (24-207): 1.8e-28: 126: 17.31