HitPredict

Interactor 1: Q9VGF9 (Q9VGF9)
Aurora kinase (EC 2.7.11.1)
Gene: aurA

Interactor 2: Q9VNE4 (Q9VNE4)
Asterless (GH02902p)
Gene: asl

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	27558293
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0007098 - centrosome cycle
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 411 Dm			1 994
+	Hs
		605578 KAPCA_HUMAN (143-406): 2.62e-131: 383: 31.23		MYH10_HUMAN (10-993): 1.78e-46: 184: 10.48
+	Hs
		563079 AURKC_HUMAN (115-411): 3.66e-130: 378: 55.33		MYH8_HUMAN (14-739): 1.58e-29: 129: 10.38
+	Hs
		773248 AURKB_HUMAN (97-411): 7.53e-106: 318: 53.46		MYH10_HUMAN (10-993): 1.78e-46: 184: 10.48
+	Hs
		651734 KAPCB_HUMAN (143-406): 2.02e-129: 378: 31.23		MYH2_HUMAN (1-637): 1.57e-23: 110: 11.04
+	Hs
		1462713 AURKC_HUMAN (115-411): 3.66e-130: 378: 55.33		MYH4_HUMAN (1-637): 3.63e-22: 105: 10.73
+	Hs
		651743 KAPCB_HUMAN (143-406): 2.02e-129: 378: 31.23		MYH4_HUMAN (1-637): 3.63e-22: 105: 10.73
+	Hs
		776870 AURKC_HUMAN (115-411): 3.66e-130: 378: 55.33		MYH11_HUMAN (502-983): 1.98e-17: 90.2: 13.79
+	Hs
		556967 AURKC_HUMAN (115-411): 3.66e-130: 378: 55.33		MYH7_HUMAN (513-994): 5.98e-15: 82.1: 8.87
+	Hs
		728066 AKT1_HUMAN (68-408): 5.1e-131: 386: 26.36		MYH9_HUMAN (1-381): 1.88e-11: 70.6: 10.37
+	Hs
		562995 KAPCB_HUMAN (143-406): 2.02e-129: 378: 31.23		MYH6_HUMAN (492-988): 1.28e-13: 77.9: 9.24
+	Hs
		556840 KAPCB_HUMAN (143-406): 2.02e-129: 378: 31.23		MYH1_HUMAN (492-986): 4.53e-13: 76: 8.67
+	Hs
		556888 AURKC_HUMAN (115-411): 3.66e-130: 378: 55.33		MYH1_HUMAN (492-986): 4.53e-13: 76: 8.67
+	Hs
		605577 KAPCA_HUMAN (143-406): 2.62e-131: 383: 31.23		MYH9_HUMAN (1-381): 1.88e-11: 70.6: 10.37
+	Hs
		587568 AKT1_HUMAN (68-408): 5.1e-131: 386: 26.36		DESP_HUMAN (123-717): 2.61e-10: 67: 14.33
+	Hs
		1277768 AURKB_HUMAN (97-411): 7.53e-106: 318: 53.46		MYH14_HUMAN (22-888): 6.67e-25: 114: 13.62
+	Dm
		356683 PLK4_DROME (151-407): 3.94e-52: 187: 38.31		Q9VNE4_DROME (1-994): 1.53e-65: 241: 100.00
+	Hs
		776845 AURKB_HUMAN (97-411): 7.53e-106: 318: 53.46		MYH11_HUMAN (502-983): 1.98e-17: 90.2: 13.79
+	Hs
		772956 AURKB_HUMAN (97-411): 7.53e-106: 318: 53.46		MYH9_HUMAN (1-381): 1.88e-11: 70.6: 10.37
+	Hs
		587768 AURKB_HUMAN (97-411): 7.53e-106: 318: 53.46		DESP_HUMAN (123-717): 2.61e-10: 67: 14.33