HitPredict

Interactor 1: Q9VJ14 (Q9VJ14)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: mib2

Interactor 2: DOS (Q9VZZ9)
Protein daughter of sevenless
Gene: DOS

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1049 Dm			1 878
+	Hs
		1091422 ANK3_HUMAN (281-1037): 3.63e-132: 445: 13.84		PHLB2_HUMAN (1-108): 5.91e-25: 114: 27.52
+	Hs
		1333096 ANR52_HUMAN (194-761): 8.12e-83: 293: 14.70		GAB2_HUMAN (3-221): 2.81e-38: 154: 30.77
+	Hs
		1295564 MIB1_HUMAN (2-585): 1.63e-75: 271: 16.69		PKHA5_HUMAN (4-309): 2.18e-41: 166: 16.20
+	Hs
		1295555 MIB1_HUMAN (2-585): 1.63e-75: 271: 16.69		PKHA4_HUMAN (7-321): 8.08e-31: 131: 15.48
+	Hs
		1434211 KDIS_HUMAN (231-668): 1.64e-67: 250: 17.73		PKHA4_HUMAN (7-321): 8.08e-31: 131: 15.48
+	Hs
		1250801 ANR50_HUMAN (161-555): 4.66e-69: 255: 15.50		MPRIP_HUMAN (8-370): 5.25e-26: 117: 15.39
+	Hs
		1295484 MIB1_HUMAN (2-585): 1.63e-75: 271: 16.69		RHG24_HUMAN (3-111): 6.94e-12: 71.4: 25.00
+	Hs
		274235 ANR17_HUMAN (238-551): 4.53e-50: 196: 14.96		PKHA4_HUMAN (7-321): 8.08e-31: 131: 15.48
+	Hs
		1234991 RAI14_HUMAN (439-593): 8.29e-09: 62: 29.03		PKHA7_HUMAN (4-399): 8.39e-49: 189: 14.96
+	Hs
		177342 ANR28_HUMAN (728-1037): 8.9e-19: 94.2: 8.86		GAB2_HUMAN (3-221): 2.81e-38: 154: 30.77
+	Hs
		1030696 ANK2_HUMAN (131-324): 1.74e-10: 67.7: 10.20		PKHA5_HUMAN (4-309): 2.18e-41: 166: 16.20
+	Hs
		177308 ANR28_HUMAN (728-1037): 8.9e-19: 94.2: 8.86		PKHA4_HUMAN (7-321): 8.08e-31: 131: 15.48
+	Hs
		1434098 RAI14_HUMAN (439-593): 8.29e-09: 62: 29.03		PKHA4_HUMAN (7-321): 8.08e-31: 131: 15.48
+	Hs
		1030662 ANK2_HUMAN (131-324): 1.74e-10: 67.7: 10.20		MPRIP_HUMAN (8-370): 5.25e-26: 117: 15.39
+	Hs
		943969 RIPK4_HUMAN (458-654): 1.82e-11: 70.5: 31.34		PHLB3_HUMAN (6-108): 6.78e-18: 90.7: 28.85
+	Hs
		1237922 Q9H4D1_HUMAN (395-654): 2.77e-11: 69.7: 26.32		PHLB3_HUMAN (6-108): 6.78e-18: 90.7: 28.85
+	Hs
		1324095 RAI14_HUMAN (439-593): 8.29e-09: 62: 29.03		RHG24_HUMAN (3-111): 6.94e-12: 71.4: 25.00