Protein: PHLB3
Pleckstrin homology-like domain family B member 3

Gene: PHLB3, PHLDB3
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q6NSJ2

Gene Ontology (top 5):
GO:0019899 - enzyme binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1153495

RAB30
Ras-related protein Rab-30

2

2

High-throughput

0.726

High

1237910

CNKR1
Connector enhancer of kinase suppressor of ras 1

2

19

High-throughput

0.726

High

1237901

SKAP1
Src kinase-associated phosphoprotein 1

2

18

High-throughput

0.705

High

710307

EPHA2
Ephrin type-A receptor 2

2

10

High-throughput

0.675

High

664927

CRHBP
Corticotropin-releasing factor-binding protein

4

1

High-throughput

0.630

High

1145875

RBP1
RalA-binding protein 1

4

8

High-throughput

0.630

High

1092979

CDC16
Cell division cycle protein 16 homolog

2

1

High-throughput

0.574

High

1128905

I13R2
Interleukin-13 receptor subunit alpha-2

2

7

High-throughput

0.574

High

329075

KLHL2
Kelch-like protein 2

2

4

High-throughput

0.558

High

1237904

MIER2
Mesoderm induction early response protein 2

2

5

High-throughput

0.558

High

447783

TPM3
Tropomyosin alpha-3 chain

2

9

High-throughput

0.553

High

1237934

CHTOP
Chromatin target of PRMT1 protein

2

1

High-throughput

0.553

High

412098

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.553

High

440119

LCK
Tyrosine-protein kinase Lck

1

10

High-throughput

0.553

High

1122403

GIT2
ARF GTPase-activating protein GIT2

1

7

High-throughput

0.553

High

1140424

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.553

High

1159504

NTRK2
BDNF/NT-3 growth factors receptor

1

17

High-throughput

0.553

High

1237899

PKN3
Serine/threonine-protein kinase N3

1

9

High-throughput

0.553

High

1237922

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

7

High-throughput

0.553

High

1028242

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.537

High

943969

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

8

High-throughput

0.514

High

296789

ST1C4
Sulfotransferase 1C4

1

1

High-throughput

0.489

High

690030

CRBB3
Beta-crystallin B3

1

3

High-throughput

0.489

High

777496

K22E
Keratin, type II cytoskeletal 2 epidermal

1

18

High-throughput

0.489

High

850783

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

2

High-throughput

0.489

High

1095889

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

2

High-throughput

0.489

High

1144029

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.489

High

1237903

SKA3
Spindle and kinetochore-associated protein 3

1

1

High-throughput

0.489

High

1237908

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

5

High-throughput

0.489

High

1237911

TRI52
E3 ubiquitin-protein ligase TRIM52

1

9

High-throughput

0.489

High

1237918

CC85A
Coiled-coil domain-containing protein 85A

1

1

High-throughput

0.489

High

1237919

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

3

High-throughput

0.489

High

1237920

DUS16
Dual specificity protein phosphatase 16

1

4

High-throughput

0.489

High

1237923

SLIK6
SLIT and NTRK-like protein 6

1

4

High-throughput

0.489

High

1237924

CPAP
Centrosomal P4.1-associated protein

1

18

High-throughput

0.489

High

1237935

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

2

High-throughput

0.489

High

242008

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

246682

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

430037

JUN
Transcription factor Jun

1

7

High-throughput

0.479

High

1237913

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

6

Small-scale

0.479

High

1237933

RCOR1
REST corepressor 1

1

5

High-throughput

0.479

High

132734

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

3

High-throughput

0.437

High

192933

CLOCK
Circadian locomoter output cycles protein kaput

1

4

High-throughput

0.437

High

217119

MS18B
Protein Mis18-beta

1

1

High-throughput

0.437

High

293852

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

372307

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.437

High

503606

TFPT
TCF3 fusion partner

1

1

High-throughput

0.437

High

567887

PRG2
Bone marrow proteoglycan

1

1

High-throughput

0.437

High

719340

MPIP3
M-phase inducer phosphatase 3

1

2

High-throughput

0.437

High

845435

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

1

High-throughput

0.437

High

959601

MAX
Protein max

1

14

High-throughput

0.437

High

1196265

GRAP1
GRIP1-associated protein 1

1

14

High-throughput

0.437

High

1201122

CCD93
Coiled-coil domain-containing protein 93

1

8

High-throughput

0.437

High

1237898

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.437

High

1237900

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.437

High

1237902

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

17

High-throughput

0.437

High

1237906

GOGA5
Golgin subfamily A member 5

1

19

High-throughput

0.437

High

1237907

CCHCR
Coiled-coil alpha-helical rod protein 1

1

11

High-throughput

0.437

High

1237909

LIPH
Lipase member H

1

1

High-throughput

0.437

High

1237912

PF21A
PHD finger protein 21A

1

7

High-throughput

0.437

High

1237916

SCLT1
Sodium channel and clathrin linker 1

1

19

High-throughput

0.437

High

1237921

NUF2
Kinetochore protein Nuf2

1

14

High-throughput

0.437

High

1237925

NCK5L
Nck-associated protein 5-like

1

1

High-throughput

0.437

High

1237926

TUFT1
Tuftelin

1

1

High-throughput

0.437

High

1237927

HM20A
High mobility group protein 20A

1

6

High-throughput

0.437

High

1237932

RABX5
Rab5 GDP/GTP exchange factor

1

2

High-throughput

0.437

High

94316

D6R9G5
Kelch like family member 2

1

8

High-throughput

0.407

High

1237929

MBIP1
MAP3K12-binding inhibitory protein 1

3

0

High-throughput

0.347

High

1195231

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.328

High

1237905

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

1237928

TNR19
Tumor necrosis factor receptor superfamily member 19

2

0

High-throughput

0.328

High

1179796

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1208293

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1211255

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.279

Low

1216368

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

1233171

ISM2
Isthmin-2

1

0

High-throughput

0.279

Low

1237930

MAP10
Microtubule-associated protein 10

1

0

High-throughput

0.279

Low

85276

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

128444

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.249

Low

340346

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.249

Low

1204649

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.249

Low

1217255

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.249

Low

1237914

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.249

Low

1237915

VPS50
Syndetin

1

0

High-throughput

0.249

Low

1237917

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.249

Low

1237931

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025