Interactor 1: Q9VJ74 (Q9VJ74)
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (DEAD box protein 23)
Gene: DmelCG10333

Interactor 2: U520 (Q9VUV9)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Protein lethal (3) 72Ab)
Gene: Brr2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 38944040
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~Sec63, BRR2_plug~Helicase_C, Helicase_C~Helicase_C, Helicase_C~Sec63
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0071011 - precatalytic spliceosome
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 822
Dm

1 2142
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025