HitPredict

Interactor 1: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Interactor 2: MED12 (Q9VW47)
Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230)
Gene: kto

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 652 Dm			1 2531
+	Dm
		674060 BRM_DROME (275-642): 1.44e-45: 176: 14.62		MED12_DROME (1-2531): 0: 2500: 100.00
+	Hs
		903506 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		CHD7_HUMAN (2113-2531): 1.04e-21: 106: 12.04
+	Hs
		1160285 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		WDR33_HUMAN (2122-2529): 5.64e-27: 123: 15.40
+	Mm
		98012 SMCA2_MOUSE (161-630): 1.45e-47: 183: 12.23		ARI1B_MOUSE (1861-2332): 5.16e-10: 67.7: 11.85
+	Mm
		60013 SMCA2_MOUSE (161-630): 1.45e-47: 183: 12.23		ARI1A_MOUSE (1909-2526): 2.08e-09: 65.7: 14.43
+	Hs
		1067270 PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79		EP300_HUMAN (2065-2529): 2.17e-11: 72.3: 14.17
+	Hs
		903203 SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30		ARI1B_HUMAN (1869-2240): 8.57e-12: 73.4: 12.90
+	Hs
		903142 SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30		EP300_HUMAN (2065-2529): 2.17e-11: 72.3: 14.17
+	Hs
		903420 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		ARI1B_HUMAN (1869-2240): 8.57e-12: 73.4: 12.90
+	Hs
		903337 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		EP300_HUMAN (2065-2529): 2.17e-11: 72.3: 14.17
+	Hs
		903220 SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30		CBP_HUMAN (1889-2525): 3.59e-10: 68: 11.63
+	Hs
		903441 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		CBP_HUMAN (1889-2525): 3.59e-10: 68: 11.63
+	Mm
		98008 SMCA4_MOUSE (149-630): 2.85e-41: 163: 14.66		ARI1B_MOUSE (1861-2332): 5.16e-10: 67.7: 11.85
+	Mm
		60006 SMCA4_MOUSE (149-630): 2.85e-41: 163: 14.66		ARI1A_MOUSE (1909-2526): 2.08e-09: 65.7: 14.43
+	Mm
		59402 SMCA4_MOUSE (149-630): 2.85e-41: 163: 14.66		CHD7_MOUSE (2255-2530): 6.71e-09: 64.2: 12.72
+	Hs
		550368 PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15		ARI1B_HUMAN (1869-2240): 8.57e-12: 73.4: 12.90
+	Hs
		550246 PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15		EP300_HUMAN (2065-2529): 2.17e-11: 72.3: 14.17
+	Hs
		1067396 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		EP300_HUMAN (2065-2529): 2.17e-11: 72.3: 14.17
+	Hs
		550367 PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15		KMT2C_HUMAN (1882-2530): 4.93e-09: 64.6: 10.03
+	Hs
		1160230 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		CBP_HUMAN (1889-2525): 3.59e-10: 68: 11.63