HitPredict

Interactor 1: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Interactor 2: MED15 (Q9Y149)
Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) (dARC105)
Gene: MED15

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 652 Dm			1 749
+	Dm
		674074 BRM_DROME (275-642): 1.44e-45: 176: 14.62		MED15_DROME (1-749): 4.01e-147: 449: 100.00
+	Hs
		1067270 PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		903142 SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		903506 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		CHD7_HUMAN (61-597): 1.04e-16: 87.3: 12.37
+	Hs
		903337 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		903220 SMCA2_HUMAN (104-630): 5.01e-43: 169: 15.30		CBP_HUMAN (136-522): 8.29e-13: 74.6: 15.25
+	Hs
		903441 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		CBP_HUMAN (136-522): 8.29e-13: 74.6: 15.25
+	Mm
		59402 SMCA4_MOUSE (149-630): 2.85e-41: 163: 14.66		CHD7_MOUSE (61-501): 1.76e-13: 76.9: 12.04
+	Hs
		323852 SC31A_HUMAN (108-527): 4.03e-42: 166: 12.45		SC24C_HUMAN (69-344): 5.24e-12: 71.6: 15.00
+	Hs
		550246 PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		550367 PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15		KMT2C_HUMAN (39-511): 2.63e-15: 82.7: 10.74
+	Hs
		1067396 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		1067507 CPSF7_HUMAN (5-560): 4.3e-33: 134: 29.89		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		1160230 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		CBP_HUMAN (136-522): 8.29e-13: 74.6: 15.25
+	Hs
		1160285 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		WDR33_HUMAN (85-485): 2.59e-10: 66.2: 21.57
+	Mm
		1455913 PCLO_MOUSE (130-453): 5.35e-13: 75.1: 16.77		PCLO_MOUSE (75-553): 7.1e-16: 84.7: 13.02
+	Dm
		119660 M9PB30_DROME (198-532): 1.27e-16: 86.7: 15.14		M9PB30_DROME (82-572): 5.3e-09: 62.3: 10.12
+	Hs
		130449 SPT5H_HUMAN (42-262): 2.87e-09: 62.4: 14.22		EP300_HUMAN (33-535): 1.46e-16: 86.6: 12.89
+	Hs
		319080 SC24D_HUMAN (180-421): 8.67e-15: 80.5: 16.11		SC31A_HUMAN (63-379): 3.8e-10: 65.8: 13.57