HitPredict

Interactor 1: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.937

The method score is based on:

Property Details
Experiments 28063214, 31152129, 10644755, 31406304, 36199071, 37689310
Identification Methods enzymatic study, affinity chromatography technology, proximity labelling technology, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Beta-TrCP_D~Beta-TrCP_D, F-box-like~F-box-like, WD40~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000209 - protein polyubiquitination
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 32 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 605
Hs

1 605
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Last updated: 11Aug2025