HitPredict

Interactor 1: PRP46 (O13615)
Pre-mRNA-splicing factor prp5 (Complexed with cdc5 protein 1) (Pre-mRNA-processing protein 5)
Gene: prp5

Interactor 2: YE02 (O13799)
Uncharacterized helicase C17H9.02 (EC 3.6.4.-)
Gene: SPAC17H9.02

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24713849
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DSHCT~WD40, Helicase_C~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 473 Sp			1 1030
+	Hs
		838770 SNR40_HUMAN (281-472): 6.16e-45: 162: 20.41		MTREX_HUMAN (28-1030): 0: 848: 46.72
+	Dm
		1488787 Q9VYQ9_DROME (1-191): 5.51e-25: 109: 8.82		Q9Y134_DROME (4-1030): 0: 817: 42.95
+	Dm
		1463928 WDS_DROME (2-152): 6.89e-20: 92.9: 9.20		Q9Y134_DROME (4-1030): 0: 817: 42.95
+	Hs
		1324983 FBXW7_HUMAN (1-312): 8.9e-65: 223: 16.57		ASCC3_HUMAN (104-654): 1.96e-106: 368: 18.14
+	Hs
		608795 FBW1A_HUMAN (103-399): 4.46e-68: 230: 25.48		DDX5_HUMAN (38-595): 2.13e-111: 359: 11.47
+	Sc
		909507 PRP46_YEAST (111-398): 1.68e-60: 206: 22.26		HFM1_YEAST (7-674): 1.43e-113: 380: 19.89
+	Hs
		1369427 FBW1A_HUMAN (103-399): 4.46e-68: 230: 25.48		DDX17_HUMAN (39-636): 5.04e-106: 349: 11.15
+	Hs
		1369337 FBXW7_HUMAN (1-312): 8.9e-65: 223: 16.57		DDX17_HUMAN (39-636): 5.04e-106: 349: 11.15
+	Hs
		141711 FBW1A_HUMAN (103-399): 4.46e-68: 230: 25.48		DDX3X_HUMAN (2-554): 3.93e-102: 336: 12.46
+	Hs
		141604 FBXW7_HUMAN (1-312): 8.9e-65: 223: 16.57		DDX3X_HUMAN (2-554): 3.93e-102: 336: 12.46
+	Sp
		150441 PRP46_SCHPO (1-473): 1.07e-117: 355: 100.00		BRR2_SCHPO (40-606): 5.38e-47: 186: 13.21
+	Hs
		608695 SNR40_HUMAN (281-472): 6.16e-45: 162: 20.41		DDX5_HUMAN (38-595): 2.13e-111: 359: 11.47
+	Hs
		289643 FBXW7_HUMAN (1-312): 8.9e-65: 223: 16.57		U520_HUMAN (40-567): 3.29e-81: 292: 19.76
+	Hs
		1369343 SNR40_HUMAN (281-472): 6.16e-45: 162: 20.41		DDX17_HUMAN (39-636): 5.04e-106: 349: 11.15
+	Hs
		289651 SNR40_HUMAN (281-472): 6.16e-45: 162: 20.41		U520_HUMAN (40-567): 3.29e-81: 292: 19.76
+	Hs
		1369406 NLE1_HUMAN (13-151): 1.7e-22: 101: 8.97		DDX17_HUMAN (39-636): 5.04e-106: 349: 11.15
+	Hs
		193129 POC1A_HUMAN (1-156): 2.52e-24: 106: 11.80		DDX3Y_HUMAN (11-554): 8.97e-102: 335: 12.74
+	Hs
		141400 WDR5_HUMAN (2-148): 6.65e-19: 89.4: 8.81		DDX3X_HUMAN (2-554): 3.93e-102: 336: 12.46
+	Hs
		289726 PRP19_HUMAN (318-473): 1.74e-19: 93: 14.72		U520_HUMAN (40-567): 3.29e-81: 292: 19.76
+	Sc
		744184 PRP46_YEAST (111-398): 1.68e-60: 206: 22.26		BRR2_YEAST (51-621): 1.13e-34: 146: 15.05