HitPredict

Interactor 1: GNB5 (O14775)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Interactor 2: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 395 Hs			1 531
+	Hs
		154696 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		154662 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		154661 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		154691 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPW_HUMAN (1-530): 0: 542: 85.85
+	Sc
		579424 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPZ_YEAST (3-530): 0: 579: 56.75
+	Sc
		579432 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPH_YEAST (2-528): 0: 543: 25.84
+	Sc
		579422 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPG_YEAST (2-527): 0: 539: 26.16
+	Hs
		1202777 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		770916 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		826748 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		921038 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		1306704 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPH_HUMAN (2-530): 0: 576: 27.93
+	Hs
		770777 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		771069 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPZ_HUMAN (1-531): 0: 573: 100.00
+	Hs
		1202774 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPW_HUMAN (1-530): 0: 542: 85.85
+	Hs
		826604 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPG_HUMAN (3-528): 0: 559: 27.96
+	Hs
		821156 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		821437 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPE_HUMAN (3-528): 0: 548: 30.47
+	Hs
		921021 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPW_HUMAN (1-530): 0: 542: 85.85
+	Hs
		821326 POC1B_HUMAN (277-395): 1.41e-31: 126: 26.89		TCPE_HUMAN (3-528): 0: 548: 30.47