Interactor 1: SOCS6 (O14544)
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)
Gene: SOCS6

Interactor 2: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 26186194, 28514442, 28883622, 12052866, 21030588
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~Skp1_POZ, SOCS_box~Skp1_POZ
Common GO terms GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 535
Hs

1 112
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Service provided by Combinatics, Japan

Last updated: 11Aug2025