HitPredict

Interactor 1: CLGN (O14967)
Calmegin
Gene: CLGN

Interactor 2: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 1255
+	Hs
		383628 CALX_HUMAN (29-610): 0: 729: 56.85		ERBB2_HUMAN (1-1255): 0: 1282: 100.00
+	Hs
		161016 CLGN_HUMAN (1-610): 0: 804: 100.00		ERBB3_HUMAN (5-1254): 0: 1041: 38.55
+	Hs
		337977 CALX_HUMAN (29-610): 0: 729: 56.85		EGFR_HUMAN (16-1253): 0: 1070: 48.40
+	Hs
		601814 CALX_HUMAN (29-610): 0: 729: 56.85		ERBB3_HUMAN (5-1254): 0: 1041: 38.55
+	Hs
		337975 CALR_HUMAN (60-456): 2.91e-129: 387: 36.00		EGFR_HUMAN (16-1253): 0: 1070: 48.40
+	Hs
		161002 CLGN_HUMAN (1-610): 0: 804: 100.00		RET_HUMAN (426-1088): 3.53e-131: 432: 23.33
+	Hs
		160999 CLGN_HUMAN (1-610): 0: 804: 100.00		INSR_HUMAN (584-1066): 2.91e-107: 371: 23.19
+	Hs
		434139 CALX_HUMAN (29-610): 0: 729: 56.85		RET_HUMAN (426-1088): 3.53e-131: 432: 23.33
+	Hs
		411305 CALX_HUMAN (29-610): 0: 729: 56.85		INSR_HUMAN (584-1066): 2.91e-107: 371: 23.19
+	Hs
		161003 CLGN_HUMAN (1-610): 0: 804: 100.00		IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92
+	Hs
		435545 CALX_HUMAN (29-610): 0: 729: 56.85		IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92
+	Rn
		544766 CALR_RAT (60-456): 5.09e-130: 389: 36.00		INSR_RAT (357-634): 2.53e-16: 87.2: 19.87