Interactor 1: GLCNE (Q9Y223)
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]
Gene: GNE
Interactor 2: GLCNE (Q9Y223)
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]
Gene: GNE
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956 |
| Identification Methods | two hybrid, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Epimerase_2~Epimerase_2, ROK~ROK |
| Common GO terms | GO:0004396 - hexokinase activity GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006045 - N-acetylglucosamine biosynthetic process and 5 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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| + | Cj |   |
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| + | Ec | |
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| + | Ec | |
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Last updated: 15 Jul 2024
