HitPredict

Interactor 1: SYNJ2 (O15056)
Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2)
Gene: SYNJ2

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	11084340, 31871319, 20936779
Identification Methods	pull down, two hybrid, affinity chromatography technology, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1496 Hs			1 192
+	Hs
		166039 SYNJ2_HUMAN (1-1496): 0: 1398: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		564747 SAC2_HUMAN (62-594): 1.9e-156: 506: 22.97		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		176425 SHIP2_HUMAN (454-1318): 6.35e-139: 462: 19.82		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		925207 OCRL_HUMAN (488-964): 5.05e-128: 422: 27.93		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		968221 OCRL_HUMAN (488-964): 5.05e-128: 422: 27.93		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892324 OCRL_HUMAN (488-964): 5.05e-128: 422: 27.93		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19