Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB
Interactor 2: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.708 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35512704 |
| Identification Methods | split luciferase complementation, anti tag coimmunoprecipitation, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~Pkinase, PK_Tyr_Ser-Thr~Pkinase |
| Common GO terms | GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 5 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
