HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: FOSL2 (P15408)
Fos-related antigen 2 (FRA-2)
Gene: FOSL2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 26496610, 25609649, 26186194, 28514442, 32296183, 9160889, 33961781, 20102225, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, peptide array, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_1
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 331
Hs

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Last updated: 15 Jul 2024