Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: LAMP1 (P11279)
Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)
Gene: LAMP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001618 - virus receptor activity
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0016020 - membrane
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 417
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024