HitPredict

Interactor 1: IKKB (O88351)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: Ikbkb

Interactor 2: TNR4 (P47741)
Tumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134)
Gene: Tnfrsf4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	21282629
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 757 Mm			1 272
+	Mm
		312125 IKKB_MOUSE (1-757): 0: 694: 100.00		TNR1A_MOUSE (8-241): 1.98e-32: 125: 22.41
+	Hs
		167814 IKKB_HUMAN (1-755): 0: 679: 92.05		TNR1A_HUMAN (8-241): 2.47e-36: 136: 19.50
+	Mm
		312127 IKKB_MOUSE (1-757): 0: 694: 100.00		TNR5_MOUSE (10-174): 2.86e-29: 113: 27.13
+	Hs
		167841 IKKB_HUMAN (1-755): 0: 679: 92.05		TNR3_HUMAN (15-173): 3.46e-29: 116: 26.49
+	Hs
		167823 IKKB_HUMAN (1-755): 0: 679: 92.05		TNR5_HUMAN (10-172): 1.11e-27: 109: 25.81
+	Hs
		167794 IKKB_HUMAN (1-755): 0: 679: 92.05		TNR16_HUMAN (27-240): 2.42e-25: 105: 22.40
+	Mm
		866564 IKKA_MOUSE (1-742): 3.47e-173: 517: 48.87		TNR4_MOUSE (1-272): 1.39e-66: 210: 100.00
+	Hs
		177792 IKKA_HUMAN (1-742): 1.91e-176: 525: 49.27		TNR1B_HUMAN (3-233): 5.07e-38: 140: 22.85
+	Hs
		177789 IKKA_HUMAN (1-742): 1.91e-176: 525: 49.27		TNR1A_HUMAN (8-241): 2.47e-36: 136: 19.50
+	Mm
		669413 IKKA_MOUSE (1-742): 3.47e-173: 517: 48.87		TNR1A_MOUSE (8-241): 1.98e-32: 125: 22.41
+	Hs
		177812 IKKA_HUMAN (1-742): 1.91e-176: 525: 49.27		TNR3_HUMAN (15-173): 3.46e-29: 116: 26.49
+	Hs
		177797 IKKA_HUMAN (1-742): 1.91e-176: 525: 49.27		TNR5_HUMAN (10-172): 1.11e-27: 109: 25.81
+	Hs
		177769 IKKA_HUMAN (1-742): 1.91e-176: 525: 49.27		TNR16_HUMAN (27-240): 2.42e-25: 105: 22.40
+	Mm
		693161 IKKA_MOUSE (1-742): 3.47e-173: 517: 48.87		TNR5_MOUSE (10-174): 2.86e-29: 113: 27.13
+	Hs
		675124 M3K5_HUMAN (14-657): 6.45e-141: 450: 19.35		TNR6_HUMAN (13-140): 1.96e-29: 115: 27.61
+	Hs
		622703 TBK1_HUMAN (15-407): 5.4e-105: 339: 26.23		TNR1A_HUMAN (8-241): 2.47e-36: 136: 19.50
+	Hs
		622611 IKKE_HUMAN (15-382): 1.14e-103: 335: 27.75		TNR1A_HUMAN (8-241): 2.47e-36: 136: 19.50