HitPredict

Interactor 1: BET1 (O15155)
BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)
Gene: BET1

Interactor 2: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 288
+	Hs
		169428 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX1B_HUMAN (1-288): 5.2e-85: 258: 83.33
+	Hs
		169389 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX2_HUMAN (1-288): 6.6e-82: 250: 63.89
+	Hs
		169451 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX3_HUMAN (1-288): 2.81e-64: 205: 62.41
+	Hs
		1017656 Q53XK0_HUMAN (1-118): 1.93e-45: 144: 100.00		STX4_HUMAN (1-287): 1.22e-63: 203: 43.58
+	Hs
		169445 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX4_HUMAN (1-287): 1.22e-63: 203: 43.58
+	Dm
		1098111 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		STX1A_DROME (2-287): 2.6e-75: 233: 69.90
+	Rn
		996537 BET1_RAT (1-118): 6.04e-46: 145: 93.22		STX5_RAT (2-267): 1.15e-51: 174: 19.16
+	Hs
		169516 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX12_HUMAN (26-271): 2.32e-51: 171: 24.50
+	Hs
		169320 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX7_HUMAN (37-286): 6.99e-50: 167: 25.30
+	Hs
		152115 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		STX16_HUMAN (15-264): 1.37e-48: 165: 22.53
+	At
		1276972 SYP61_ARATH (11-117): 8.06e-29: 106: 20.91		SY121_ARATH (19-266): 2.64e-58: 191: 22.27
+	At
		249582 SYP61_ARATH (11-117): 8.06e-29: 106: 20.91		SYP41_ARATH (29-287): 3.69e-52: 175: 20.76
+	At
		1276970 SYP61_ARATH (11-117): 8.06e-29: 106: 20.91		SYP43_ARATH (10-287): 2.85e-51: 172: 18.31
+	At
		1276971 SYP61_ARATH (11-117): 8.06e-29: 106: 20.91		SYP42_ARATH (30-287): 2.78e-51: 172: 21.59
+	Dm
		1098012 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		STX5_DROME (2-268): 2.15e-51: 176: 16.61
+	Mm
		1206470 STX6_MOUSE (10-97): 1.68e-20: 84.6: 19.32		Q8BH40_MOUSE (37-288): 4.59e-58: 188: 25.49
+	Rn
		192328 BET1L_RAT (26-114): 9.01e-22: 84.6: 36.26		STX5_RAT (2-267): 1.15e-51: 174: 19.16
+	Hs
		178319 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		STX7_HUMAN (37-286): 6.99e-50: 167: 25.30
+	Hs
		152120 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		STX16_HUMAN (15-264): 1.37e-48: 165: 22.53
+	At
		955675 SYP52_ARATH (28-117): 3.86e-20: 83.5: 18.09		SYP22_ARATH (14-272): 1.29e-48: 164: 18.89