HitPredict

Interactor 1: GFPT2 (O94808)
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)
Gene: GFPT2

Interactor 2: GFPT1 (Q06210)
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 1) (Glutamine:fructose-6-phosphate amidotransferase 1) (GFAT 1) (GFAT1) (Hexosephosphate aminotransferase 1)
Gene: GFPT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GATase_6~GATase_6, GATase_6~SIS, SIS~SIS
Common GO terms GO:0004360 - glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0005829 - cytosol
GO:0006002 - fructose 6-phosphate metabolic process
GO:0006047 - UDP-N-acetylglucosamine metabolic process
GO:0006048 - UDP-N-acetylglucosamine biosynthetic process
and 4 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 682
Hs

1 699
+ Hs
+ Ce
+ Ca
+ Ec
+ Cj
+ Sc
+ Ec
+ Sp
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024