Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPA49 (Q9GZS1)
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
Gene: POLR1E

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.747

The method score is based on:

Property Details
Experiments 28514442, 9254723, 24981860, 33961781, 35271311, 17353931, 15226435
Identification Methods affinity chromatography technology, biochemical, far western blotting, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001650 - fibrillar center
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 346
Hs

1 419
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024