HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 24981860, 35271311, 33674783, 28514442, 33961781
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb2_6
Common GO terms GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 346
Hs

1 1133
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+ Dm
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+ Sc
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+ Sc
+ Sc
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+ Sp
+ Pf
+ Hs
+ Sc
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+ Hv
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024