Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.992

The method score is based on:

Property Details
Experiments 27902311, 9734785, 30181396, 29789528, 32533114, 34079125, 10228155, 20531388, 26496610, 29045831, 19223551, 12805222, 35530152, 16199882, 12421363, 18632848, 19131971, 22509369, 20128690, 18593713 and 11 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Axin_b-cat_bind
Common GO terms GO:0000209 - protein polyubiquitination
GO:0001701 - in utero embryonic development
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 17 others

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Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 862
Hs

1 781
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024