Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: KC1A (P48729)
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.860

The method score is based on:

Property Details
Experiments 26496610, 11884395, 17510365, 22682247
Identification Methods affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RGS
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0030877 - beta-catenin destruction complex
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 862
Hs

1 337
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024