Interactor 1: STX2 (P32856)
Syntaxin-2 (Epimorphin)
Gene: STX2

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 29360461, 12828989, 32296183, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Synaptobrevin, Synaptobrevin~Syntaxin
Common GO terms GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
GO:0008021 - synaptic vesicle
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 288
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024