HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: RAI14 (Q9P0K7)
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)
Gene: RAI14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	1.00	0.715

Property	Details
Experiments	28330616
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_5
Common GO terms	GO:0001725 - stress fiber GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 980
+	Hs
		171296 MYPT1_HUMAN (1-1030): 1.9e-151: 478: 100.00		MY18A_HUMAN (351-942): 3.05e-73: 267: 19.06
+	Hs
		171318 MYPT1_HUMAN (1-1030): 1.9e-151: 478: 100.00		UACA_HUMAN (411-974): 2.31e-39: 161: 24.63
+	Hs
		171348 MYPT1_HUMAN (1-1030): 1.9e-151: 478: 100.00		ANR50_HUMAN (67-280): 1.06e-34: 146: 23.36
+	Hs
		1453796 ANR50_HUMAN (1-837): 1.75e-93: 328: 14.03		RAI14_HUMAN (1-980): 1.22e-80: 284: 100.00
+	Mm
		1036444 ANS1B_MOUSE (44-816): 4.89e-79: 284: 17.01		ANK1_MOUSE (21-404): 2.13e-52: 202: 19.13
+	Hs
		1047634 NOTC2_HUMAN (8-636): 5.32e-77: 279: 19.14		ANR44_HUMAN (5-217): 5.07e-48: 187: 26.77
+	Hs
		177330 ANR50_HUMAN (1-837): 1.75e-93: 328: 14.03		ANR28_HUMAN (126-395): 5.7e-25: 114: 18.52
+	Hs
		177261 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		ANR44_HUMAN (5-217): 5.07e-48: 187: 26.77
+	Hs
		177209 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		ANK3_HUMAN (60-412): 3.93e-42: 170: 21.25
+	Hs
		177304 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		UACA_HUMAN (411-974): 2.31e-39: 161: 24.63
+	Hs
		177204 NOTC2_HUMAN (8-636): 5.32e-77: 279: 19.14		ANR28_HUMAN (126-395): 5.7e-25: 114: 18.52
+	Hs
		177291 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		EHMT2_HUMAN (1-122): 1.03e-27: 123: 27.64
+	Hs
		177135 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		ANR28_HUMAN (126-395): 5.7e-25: 114: 18.52
+	Hs
		177263 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		ANR52_HUMAN (122-362): 7.09e-22: 104: 18.26
+	Hs
		274188 ANKH1_HUMAN (21-921): 7.6e-66: 245: 13.08		ANR17_HUMAN (32-258): 1.85e-20: 100: 22.46
+	Hs
		177170 ANR28_HUMAN (1-342): 3.52e-65: 241: 18.32		BCL3_HUMAN (34-213): 6.21e-20: 95.9: 32.97