HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: WIPI4 (Q9Y484)
WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45)
Gene: WDR45

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 360
+	Hs
		173205 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SNR40_HUMAN (34-350): 8.5e-58: 193: 12.65
+	Hs
		173175 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FBXW7_HUMAN (5-260): 1.02e-39: 151: 16.35
+	Hs
		173328 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SKI8_HUMAN (117-274): 6.86e-36: 134: 20.89
+	Xl
		1232829 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		SKI8_XENLA (117-274): 1.26e-34: 131: 18.35
+	Hs
		173367 XPO1_HUMAN (1-1071): 0: 1022: 100.00		BCAS3_HUMAN (151-271): 1.02e-24: 107: 21.54
+	Hs
		172318 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TBL1X_HUMAN (136-356): 3.67e-23: 102: 12.93
+	Hs
		172877 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SMU1_HUMAN (8-265): 4.68e-20: 93.3: 9.16
+	Hs
		173321 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TBL1R_HUMAN (187-340): 2.6e-15: 78.8: 13.19
+	Xl
		1237610 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		SMU1_XENLA (8-265): 6.88e-19: 89.8: 9.16
+	Hs
		172647 XPO1_HUMAN (1-1071): 0: 1022: 100.00		WDR5_HUMAN (3-126): 1.52e-11: 66.4: 10.69
+	Xl
		1237683 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		TB1RA_XENLA (187-340): 2.17e-15: 79.2: 13.19
+	Xl
		1237768 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q8AVP6_XENLA (7-267): 3.14e-14: 74.4: 12.27
+	Xl
		1231406 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6DCY8_XENLA (3-126): 1.54e-10: 63.7: 10.69
+	Sc
		722088 XPO1_YEAST (14-1067): 0: 848: 46.08		HSV2_YEAST (1-302): 2.81e-63: 209: 31.49
+	Sc
		721870 XPO1_YEAST (14-1067): 0: 848: 46.08		TAF5_YEAST (181-356): 1.35e-25: 109: 12.07
+	Hs
		1460326 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		WIPI4_HUMAN (1-360): 6.79e-93: 283: 100.00
+	Hs
		1460332 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		WIPI2_HUMAN (7-357): 3.23e-89: 277: 20.77
+	Hs
		220961 XPOT_HUMAN (29-1023): 3.56e-126: 410: 14.85		FBXW7_HUMAN (5-260): 1.02e-39: 151: 16.35
+	Hs
		1435212 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		BCAS3_HUMAN (151-271): 1.02e-24: 107: 21.54
+	Mm
		965404 XPO7_MOUSE (23-1013): 5.45e-120: 397: 13.01		WDR5_MOUSE (3-126): 1.52e-11: 66.4: 10.69