HitPredict

Interactor 1: DCLK1 (O15075)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 740 Hs			1 1098
+	Hs
		1327406 DCLK2_HUMAN (1-725): 0: 799: 66.36		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Hs
		176869 DCLK1_HUMAN (1-740): 0: 895: 100.00		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Mm
		1247223 DCLK1_MOUSE (1-740): 0: 882: 96.43		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		176809 DCLK1_HUMAN (1-740): 0: 895: 100.00		AFAD_HUMAN (419-593): 1.97e-23: 110: 30.11
+	Hs
		1327403 DCLK2_HUMAN (1-725): 0: 799: 66.36		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Hs
		1091563 M3K3_HUMAN (51-646): 9.47e-142: 431: 18.59		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Mm
		313043 DCX_MOUSE (6-363): 6.61e-135: 404: 69.40		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Mm
		1223567 KCC2D_MOUSE (385-737): 8.01e-131: 398: 33.05		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Mm
		313044 DCX_MOUSE (6-363): 6.61e-135: 404: 69.40		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		221285 DCX_HUMAN (6-344): 5.89e-134: 402: 72.33		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Mm
		1244501 KCC2D_MOUSE (385-737): 8.01e-131: 398: 33.05		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Rn
		204571 KCC2D_RAT (385-732): 4.82e-127: 390: 34.94		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Mm
		1223775 KS6A2_MOUSE (388-680): 2.78e-99: 324: 27.24		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Mm
		266786 KCC2D_MOUSE (385-737): 8.01e-131: 398: 33.05		LNX1_MOUSE (39-594): 1.45e-31: 134: 12.15
+	Rn
		540173 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		DLG3_RAT (311-1098): 3.58e-74: 265: 12.84
+	Rn
		540169 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		DLG1_RAT (225-1097): 2.72e-72: 261: 13.46
+	Hs
		1119728 KCC1A_HUMAN (378-690): 4.72e-135: 405: 40.95		IL16_HUMAN (152-648): 4.77e-09: 62.9: 16.31
+	Rn
		204569 KCC2G_RAT (387-647): 1.29e-64: 225: 43.77		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Rn
		204568 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Rn
		540159 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		SAM14_RAT (920-1075): 3.4e-35: 141: 47.47