Protein: ID3
DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3) (Inhibitor of differentiation 3)

Gene: ID3
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q02535

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001656 - metanephros development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551119

ITF2
Transcription factor 4

8

20

Small-scale

0.976

High

551503

TFE2
Transcription factor E2-alpha

8

20

Small-scale

0.972

High

971137

HTF4
Transcription factor 12

7

20

Small-scale

0.962

High

971120

FHL2
Four and a half LIM domains protein 2

3

4

Small-scale

0.853

High

63045

MSGN1
Mesogenin-1

2

19

High-throughput

0.783

High

526744

MYF5
Myogenic factor 5

2

17

High-throughput

0.783

High

903703

LMO4
LIM domain transcription factor LMO4

2

4

High-throughput

0.783

High

971116

ID3
DNA-binding protein inhibitor ID-3

1

4

Small-scale

0.656

High

971142

MLX
Max-like protein X

1

3

Small-scale

0.656

High

738957

SRBP1
Sterol regulatory element-binding protein 1

1

1

Small-scale

0.647

High

971135

PDLI5
PDZ and LIM domain protein 5

1

2

Small-scale

0.647

High

524557

LYL1
Protein lyl-1

1

20

High-throughput

0.618

High

545959

MYOD1
Myoblast determination protein 1

1

13

Small-scale

0.618

High

207308

FRS3
Fibroblast growth factor receptor substrate 3

2

1

High-throughput

0.606

High

829825

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.606

High

971134

KAT5
Histone acetyltransferase KAT5

2

1

High-throughput

0.606

High

132829

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

971118

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.580

High

798865

GATA4
Transcription factor GATA-4

1

2

Small-scale

0.561

High

971141

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

2

Small-scale

0.561

High

971128

CV039
Synaptic plasticity regulator PANTS

2

1

High-throughput

0.553

High

203447

MTG8R
Protein CBFA2T2

1

5

High-throughput

0.541

High

971123

E2F4
Transcription factor E2F4

1

1

High-throughput

0.541

High

971138

PRD14
PR domain zinc finger protein 14

1

2

High-throughput

0.541

High

971144

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.541

High

265190

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.518

High

971130

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

563777

ZNF3
Zinc finger protein 3

1

1

Small-scale

0.508

High

579195

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

1

Small-scale

0.508

High

782775

CSK
Tyrosine-protein kinase CSK

1

1

Small-scale

0.508

High

971140

ZN408
Zinc finger protein 408

1

1

Small-scale

0.508

High

625376

CDK2
Cyclin-dependent kinase 2

1

4

Small-scale

0.501

High

257346

CNOT3
CCR4-NOT transcription complex subunit 3

1

0

Small-scale

0.486

High

971126

ZN626
Zinc finger protein 626

1

0

Small-scale

0.486

High

971143

PUF60
Poly(U)-binding-splicing factor PUF60

1

0

Small-scale

0.486

High

921534

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

Small-scale

0.481

High

971132

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

1

High-throughput

0.481

High

771922

VHL
von Hippel-Lindau disease tumor suppressor

1

2

Small-scale

0.479

High

858092

NKX25
Homeobox protein Nkx-2.5

1

2

Small-scale

0.479

High

971121

ELOC
Elongin-C

1

2

Small-scale

0.479

High

971124

Q49AR9
ANKS1A protein

1

1

High-throughput

0.470

High

971139

BOLA2
BolA-like protein 2

1

0

High-throughput

0.460

High

971117

PAX5
Paired box protein Pax-5

1

0

Small-scale

0.458

High

971122

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

971119

MTG8
Protein CBFA2T1

1

5

High-throughput

0.457

High

971131

TSC1
Hamartin

1

0

Small-scale

0.438

High

971127

Q6FHM2
Epididymis secretory sperm binding protein

1

1

Small-scale

0.417

High

971129

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.316

High

971136

GUCD1
Protein GUCD1

2

0

High-throughput

0.316

High

760

A0A087WZT3
BOLA2-SMG1P6 readthrough

1

0

High-throughput

0.268

Low

103724

G5E9A7
DM1 locus, WD repeat containing

1

0

High-throughput

0.268

Low

844882

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.268

Low

971125

F74A1
Protein FAM74A1

1

0

High-throughput

0.268

Low

971133

RND1
Rho-related GTP-binding protein Rho6

1

0

Small-scale

0.265

Low


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Last updated: 15 Jul 2024