HitPredict

Interactor 1: EIF3H (O15372)
Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit)
Gene: EIF3H

Interactor 2: EIF3C (Q99613)
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110)
Gene: EIF3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 33961781, 35235311, 26186194, 28514442, 32269044, 24981860, 19615732, 23623729
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~PCI
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex
and 3 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 352
Hs

1 913
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024