HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	24722339
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 428 Hs			1 127
+	Hs
		1038424 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		707620 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		918340 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1038606 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1270408 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2B1M_HUMAN (1-127): 6.74e-55: 169: 84.25
+	Hs
		1087306 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		1038530 HDAC1_HUMAN (3-385): 0: 588: 62.92		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Hs
		707699 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		1270361 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1270409 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		1231218 HDAC2_HUMAN (3-422): 0: 580: 58.63		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Sp
		140569 PHD1_SCHPO (3-407): 0: 519: 56.27		H2B1_SCHPO (5-126): 8.55e-46: 146: 69.67
+	At
		1322590 HDA6_ARATH (3-423): 0: 520: 55.32		H2B10_ARATH (37-126): 2.54e-42: 138: 78.89
+	Sc
		355947 HOS2_YEAST (4-420): 1.09e-174: 497: 50.36		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Hs
		1307130 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		H2B1M_HUMAN (1-127): 6.74e-55: 169: 84.25
+	Hs
		241656 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		707778 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		886211 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		1307148 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Sc
		355966 HDA1_YEAST (4-351): 1.16e-115: 355: 21.56		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36