HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: SMD1 (P62314)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)
Gene: SNRPD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 133 Hs			1 119
+	Hs
		178060 LSM1_HUMAN (1-133): 3.58e-53: 165: 100.00		LSM4_HUMAN (1-89): 1.25e-33: 115: 23.33
+	Hs
		178058 LSM1_HUMAN (1-133): 3.58e-53: 165: 100.00		LSM2_HUMAN (1-88): 7.65e-33: 111: 31.11
+	Hs
		178009 LSM1_HUMAN (1-133): 3.58e-53: 165: 100.00		RUXF_HUMAN (3-69): 8.63e-27: 96.6: 28.36
+	Dm
		1479999 Q9W2K2_DROME (1-124): 3.54e-39: 130: 63.71		Q9VKW8_DROME (1-100): 2.73e-34: 117: 24.75
+	Dm
		1486292 Q9W2K2_DROME (1-124): 3.54e-39: 130: 63.71		Q9VTW6_DROME (1-88): 7.12e-34: 114: 31.11
+	Dm
		1479993 Q9W087_DROME (8-97): 1.71e-31: 109: 26.37		Q9VKW8_DROME (1-100): 2.73e-34: 117: 24.75
+	Hs
		344528 LSM8_HUMAN (7-95): 2.26e-31: 108: 33.33		SMD1_HUMAN (1-96): 1.19e-34: 117: 100.00
+	Dm
		1486290 Q9W087_DROME (8-97): 1.71e-31: 109: 26.37		Q9VTW6_DROME (1-88): 7.12e-34: 114: 31.11
+	Hs
		344583 LSM8_HUMAN (7-95): 2.26e-31: 108: 33.33		LSM4_HUMAN (1-89): 1.25e-33: 115: 23.33
+	Hs
		344579 LSM8_HUMAN (7-95): 2.26e-31: 108: 33.33		LSM2_HUMAN (1-88): 7.65e-33: 111: 31.11
+	Sc
		795885 LSM1_YEAST (4-123): 5.09e-34: 118: 40.98		LSM2_YEAST (1-87): 1.39e-28: 101: 28.09
+	Hs
		344529 LSM8_HUMAN (7-95): 2.26e-31: 108: 33.33		SMD3_HUMAN (2-102): 1.07e-31: 110: 28.71
+	At
		1425523 Q9FI15_ARATH (4-93): 1.79e-25: 98.5: 22.00		SMD1B_ARATH (1-99): 9.55e-35: 117: 71.72
+	Hs
		974491 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		SMD1_HUMAN (1-96): 1.19e-34: 117: 100.00
+	Hs
		1460921 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		LSM4_HUMAN (1-89): 1.25e-33: 115: 23.33
+	Hs
		1460917 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		LSM2_HUMAN (1-88): 7.65e-33: 111: 31.11
+	Hs
		974864 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		SMD3_HUMAN (2-102): 1.07e-31: 110: 28.71
+	Hs
		344525 LSM8_HUMAN (7-95): 2.26e-31: 108: 33.33		RUXF_HUMAN (3-69): 8.63e-27: 96.6: 28.36
+	Hs
		974076 LSM7_HUMAN (8-89): 4.36e-27: 98.5: 29.89		RUXF_HUMAN (3-69): 8.63e-27: 96.6: 28.36
+	Sc
		818014 LSM1_YEAST (4-123): 5.09e-34: 118: 40.98		LSM4_YEAST (1-76): 3.82e-15: 69.3: 27.59