HitPredict

Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: NSD1 (Q96L73)
Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.357) (Androgen receptor coactivator 267 kDa protein) (Androgen receptor-associated protein of 267 kDa) (H3-K36-HMTase) (Lysine N-methyltransferase 3B) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein)
Gene: NSD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 2696
+	Hs
		1056940 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		NSD1_HUMAN (1-2696): 0: 3408: 100.00
+	Hs
		179513 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		NSD2_HUMAN (162-430): 3.61e-72: 270: 24.63
+	Hs
		179824 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		EHMT1_HUMAN (1781-2098): 2.45e-65: 247: 20.29
+	Hs
		179804 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		NSD3_HUMAN (130-430): 6.42e-60: 231: 24.92
+	Hs
		331865 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		NSD2_HUMAN (162-430): 3.61e-72: 270: 24.63
+	Hs
		331812 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		NSD2_HUMAN (162-430): 3.61e-72: 270: 24.63
+	Hs
		1295406 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		EHMT1_HUMAN (1781-2098): 2.45e-65: 247: 20.29
+	Hs
		1295391 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		EHMT2_HUMAN (1826-2080): 8.77e-63: 239: 22.49
+	Hs
		1056971 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		SETD2_HUMAN (1790-2119): 9.55e-63: 241: 27.98
+	Dm
		332876 Q9VPR2_DROME (63-508): 6.41e-26: 113: 11.60		CHDM_DROME (2112-2230): 8.61e-34: 146: 27.56