HitPredict

Interactor 1: EPHB6 (O15197)
Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)
Gene: EPHB6

Interactor 2: GOPC (Q9HD26)
Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST)
Gene: GOPC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_2
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1021 Hs			1 462
+	Hs
		710896 EPHB2_HUMAN (33-1020): 0: 1118: 45.97		GOPC_HUMAN (1-462): 7.01e-111: 337: 100.00
+	Hs
		932138 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		GOPC_HUMAN (1-462): 7.01e-111: 337: 100.00
+	Hs
		1147439 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		GOPC_HUMAN (1-462): 7.01e-111: 337: 100.00
+	Hs
		710664 EPHA3_HUMAN (30-1021): 0: 1098: 38.87		GOPC_HUMAN (1-462): 7.01e-111: 337: 100.00
+	Hs
		710901 EPHB2_HUMAN (33-1020): 0: 1118: 45.97		LIN7C_HUMAN (280-393): 5.98e-35: 130: 38.60
+	Hs
		932143 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		LIN7C_HUMAN (280-393): 5.98e-35: 130: 38.60
+	Hs
		1147448 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		LIN7C_HUMAN (280-393): 5.98e-35: 130: 38.60
+	Hs
		710866 EPHB2_HUMAN (33-1020): 0: 1118: 45.97		LNX1_HUMAN (163-462): 1.64e-21: 99.7: 12.82
+	Hs
		932104 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		PARD3_HUMAN (223-459): 1.25e-21: 100: 19.76
+	Hs
		932103 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		LNX1_HUMAN (163-462): 1.64e-21: 99.7: 12.82
+	Hs
		710820 EPHB2_HUMAN (33-1020): 0: 1118: 45.97		PTN13_HUMAN (17-377): 1.68e-17: 87.8: 10.80
+	Hs
		1147390 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		PARD3_HUMAN (223-459): 1.25e-21: 100: 19.76
+	Hs
		1147388 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		LNX1_HUMAN (163-462): 1.64e-21: 99.7: 12.82
+	Hs
		931816 EPHB3_HUMAN (28-1021): 0: 1104: 44.44		LNX1_HUMAN (163-462): 1.64e-21: 99.7: 12.82
+	Hs
		932061 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		PTN13_HUMAN (17-377): 1.68e-17: 87.8: 10.80
+	Hs
		710645 EPHA3_HUMAN (30-1021): 0: 1098: 38.87		PARD3_HUMAN (223-459): 1.25e-21: 100: 19.76
+	Hs
		1147375 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		LNX2_HUMAN (256-461): 8.09e-18: 88.2: 18.22
+	Hs
		1090129 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		PTN13_HUMAN (17-377): 1.68e-17: 87.8: 10.80
+	Hs
		710622 EPHA3_HUMAN (30-1021): 0: 1098: 38.87		PTN13_HUMAN (17-377): 1.68e-17: 87.8: 10.80
+	Hs
		932093 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		MAGI2_HUMAN (217-433): 3.18e-11: 68.1: 14.67