HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29121065
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0098686 - hippocampal mossy fiber to CA3 synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 998 Hs			1 728
+	Hs
		1147375 EPHA7_HUMAN (1-998): 0: 1312: 100.00		LNX2_HUMAN (3-728): 2.41e-118: 372: 45.48
+	Hs
		932103 EPHA4_HUMAN (4-998): 0: 1233: 62.29		LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00
+	Hs
		710866 EPHB2_HUMAN (32-995): 0: 1192: 57.51		LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00
+	Hs
		931816 EPHB3_HUMAN (29-996): 0: 1136: 55.52		LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00
+	Hs
		1122235 EPHA7_HUMAN (1-998): 0: 1312: 100.00		SCRIB_HUMAN (355-725): 8.93e-41: 163: 21.25
+	Hs
		1147390 EPHA7_HUMAN (1-998): 0: 1312: 100.00		PARD3_HUMAN (247-554): 1.4e-32: 137: 20.96
+	Hs
		1091501 EPHA7_HUMAN (1-998): 0: 1312: 100.00		DLG1_HUMAN (477-728): 1.31e-31: 134: 21.88
+	Hs
		1090129 EPHA7_HUMAN (1-998): 0: 1312: 100.00		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Hs
		932104 EPHA4_HUMAN (4-998): 0: 1233: 62.29		PARD3_HUMAN (247-554): 1.4e-32: 137: 20.96
+	Hs
		932062 EPHA4_HUMAN (4-998): 0: 1233: 62.29		DLG1_HUMAN (477-728): 1.31e-31: 134: 21.88
+	Hs
		710831 EPHB2_HUMAN (32-995): 0: 1192: 57.51		SCRIB_HUMAN (355-725): 8.93e-41: 163: 21.25
+	Hs
		932061 EPHA4_HUMAN (4-998): 0: 1233: 62.29		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Hs
		931873 EPHA5_HUMAN (6-988): 0: 1209: 62.74		PARD3_HUMAN (247-554): 1.4e-32: 137: 20.96
+	Hs
		710645 EPHA3_HUMAN (25-990): 0: 1206: 62.01		PARD3_HUMAN (247-554): 1.4e-32: 137: 20.96
+	Hs
		931842 EPHA5_HUMAN (6-988): 0: 1209: 62.74		DLG1_HUMAN (477-728): 1.31e-31: 134: 21.88
+	Hs
		931840 EPHA5_HUMAN (6-988): 0: 1209: 62.74		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Hs
		932093 EPHA4_HUMAN (4-998): 0: 1233: 62.29		MAGI2_HUMAN (94-504): 6.37e-19: 94: 10.17
+	Hs
		710622 EPHA3_HUMAN (25-990): 0: 1206: 62.01		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Hs
		710820 EPHB2_HUMAN (32-995): 0: 1192: 57.51		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Mm
		932046 EPHB2_MOUSE (32-996): 0: 1195: 57.35		GRIP1_MOUSE (507-720): 2.08e-12: 72.8: 28.84